Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents

Farzaneh Bagherzadeh; Mehrangiz Ebrahimi-Mameghani; Mohammad Asghari Jafarabadi; Zahra Aslani; Sare Edalati

doi:doi:10.11648/j.ajbio.s.2015030202.11

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Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents

Farzaneh Bagherzadeh, Mehrangiz Ebrahimi-Mameghani, Mohammad Asghari Jafarabadi, Zahra Aslani, Sare Edalati

Published in International Journal of Nutrition and Food Sciences (Volume 4, Issue 2-1)

Received: 20 December 2014 Accepted: 25 January 2015 Published: 2 March 2015

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Abstract

Reactive oxygen species (ROS) and oxidative stress (OS) have important role in prevention, initiation and progression of chronic diseases from early childhood, but OS status in healthy young subjects and appropriate methods for its measurement have been remained unclear. Evaluation of urinary biomarker set for OS has not been well documented in Iran. In this study, evaluation of OS from urinary biomarker in healthy adolescents and its relevance to anthropometric index were investigated. Forty- hundred students aged 13 and 19 years old participated in this study. 8-hydroxy-2ʹ-deoxyguanosine (8-OHdG) as marker of oxidative DNA damage was measured in adolescents and also its relation with age, sex and body mass index was studied. Subjects were sampled by multistage cluster sampling. The average ratio of 8-OHdG to creatinine was 4.7±4.1.No significant difference of 8-OHdG was observed between boys and girls in this study.

Published in	International Journal of Nutrition and Food Sciences (Volume 4, Issue 2-1) This article belongs to the Special Issue Functional Foods and Nutraceuticals for Management of Type 2 Diabetes
DOI	10.11648/j.ajbio.s.2015030202.11
Page(s)	21-25
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Oxidative Stress, Oxidative DNA Damage, Adolescents, Body Mass Index, Age, Sex

References

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APA Style

Farzaneh Bagherzadeh, Mehrangiz Ebrahimi-Mameghani, Mohammad Asghari Jafarabadi, Zahra Aslani, Sare Edalati. (2015). Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents. International Journal of Nutrition and Food Sciences, 4(2-1), 21-25. https://doi.org/10.11648/j.ajbio.s.2015030202.11

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ACS Style

Farzaneh Bagherzadeh; Mehrangiz Ebrahimi-Mameghani; Mohammad Asghari Jafarabadi; Zahra Aslani; Sare Edalati. Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents. Int. J. Nutr. Food Sci. 2015, 4(2-1), 21-25. doi: 10.11648/j.ajbio.s.2015030202.11

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AMA Style

Farzaneh Bagherzadeh, Mehrangiz Ebrahimi-Mameghani, Mohammad Asghari Jafarabadi, Zahra Aslani, Sare Edalati. Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents. Int J Nutr Food Sci. 2015;4(2-1):21-25. doi: 10.11648/j.ajbio.s.2015030202.11

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@article{10.11648/j.ajbio.s.2015030202.11,
  author = {Farzaneh Bagherzadeh and Mehrangiz Ebrahimi-Mameghani and Mohammad Asghari Jafarabadi and Zahra Aslani and Sare Edalati},
  title = {Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {4},
  number = {2-1},
  pages = {21-25},
  doi = {10.11648/j.ajbio.s.2015030202.11},
  url = {https://doi.org/10.11648/j.ajbio.s.2015030202.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.s.2015030202.11},
  abstract = {Reactive oxygen species (ROS) and oxidative stress (OS) have important role in prevention, initiation and progression of chronic diseases from early childhood, but OS status in healthy young subjects and appropriate methods for its measurement have been remained unclear. Evaluation of urinary biomarker set for OS has not been well documented in Iran. In this study, evaluation of OS from urinary biomarker in healthy adolescents and its relevance to anthropometric index were investigated. Forty- hundred students aged 13 and 19 years old participated in this study. 8-hydroxy-2ʹ-deoxyguanosine (8-OHdG) as marker of oxidative DNA damage was measured in adolescents and also its relation with age, sex and body mass index was studied. Subjects were sampled by multistage cluster sampling. The average ratio of 8-OHdG to creatinine was 4.7±4.1.No significant difference of 8-OHdG was observed between boys and girls in this study.},
 year = {2015}
}

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TY  - JOUR
T1  - Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents
AU  - Farzaneh Bagherzadeh
AU  - Mehrangiz Ebrahimi-Mameghani
AU  - Mohammad Asghari Jafarabadi
AU  - Zahra Aslani
AU  - Sare Edalati
Y1  - 2015/03/02
PY  - 2015
N1  - https://doi.org/10.11648/j.ajbio.s.2015030202.11
DO  - 10.11648/j.ajbio.s.2015030202.11
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 21
EP  - 25
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ajbio.s.2015030202.11
AB  - Reactive oxygen species (ROS) and oxidative stress (OS) have important role in prevention, initiation and progression of chronic diseases from early childhood, but OS status in healthy young subjects and appropriate methods for its measurement have been remained unclear. Evaluation of urinary biomarker set for OS has not been well documented in Iran. In this study, evaluation of OS from urinary biomarker in healthy adolescents and its relevance to anthropometric index were investigated. Forty- hundred students aged 13 and 19 years old participated in this study. 8-hydroxy-2ʹ-deoxyguanosine (8-OHdG) as marker of oxidative DNA damage was measured in adolescents and also its relation with age, sex and body mass index was studied. Subjects were sampled by multistage cluster sampling. The average ratio of 8-OHdG to creatinine was 4.7±4.1.No significant difference of 8-OHdG was observed between boys and girls in this study.
VL  - 4
IS  - 2-1
ER  -

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Author Information

Farzaneh Bagherzadeh

Department of Nutrition in Society, Nutrition Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
Mehrangiz Ebrahimi-Mameghani

Department of Nutrition in Society, Nutrition Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
Mohammad Asghari Jafarabadi

Medical Education Research Center, Department of Statistics and Epidemiology, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran
Zahra Aslani

Nutrition and Endocrine Research Center, and Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Sare Edalati

Department of Nutrition in Society, Nutrition Faculty, Tabriz University of Medical Sciences, Tabriz, Iran

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APA Style

Farzaneh Bagherzadeh, Mehrangiz Ebrahimi-Mameghani, Mohammad Asghari Jafarabadi, Zahra Aslani, Sare Edalati. (2015). Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents. International Journal of Nutrition and Food Sciences, 4(2-1), 21-25. https://doi.org/10.11648/j.ajbio.s.2015030202.11

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ACS Style

Farzaneh Bagherzadeh; Mehrangiz Ebrahimi-Mameghani; Mohammad Asghari Jafarabadi; Zahra Aslani; Sare Edalati. Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents. Int. J. Nutr. Food Sci. 2015, 4(2-1), 21-25. doi: 10.11648/j.ajbio.s.2015030202.11

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AMA Style

Farzaneh Bagherzadeh, Mehrangiz Ebrahimi-Mameghani, Mohammad Asghari Jafarabadi, Zahra Aslani, Sare Edalati. Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents. Int J Nutr Food Sci. 2015;4(2-1):21-25. doi: 10.11648/j.ajbio.s.2015030202.11

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@article{10.11648/j.ajbio.s.2015030202.11,
  author = {Farzaneh Bagherzadeh and Mehrangiz Ebrahimi-Mameghani and Mohammad Asghari Jafarabadi and Zahra Aslani and Sare Edalati},
  title = {Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {4},
  number = {2-1},
  pages = {21-25},
  doi = {10.11648/j.ajbio.s.2015030202.11},
  url = {https://doi.org/10.11648/j.ajbio.s.2015030202.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.s.2015030202.11},
  abstract = {Reactive oxygen species (ROS) and oxidative stress (OS) have important role in prevention, initiation and progression of chronic diseases from early childhood, but OS status in healthy young subjects and appropriate methods for its measurement have been remained unclear. Evaluation of urinary biomarker set for OS has not been well documented in Iran. In this study, evaluation of OS from urinary biomarker in healthy adolescents and its relevance to anthropometric index were investigated. Forty- hundred students aged 13 and 19 years old participated in this study. 8-hydroxy-2ʹ-deoxyguanosine (8-OHdG) as marker of oxidative DNA damage was measured in adolescents and also its relation with age, sex and body mass index was studied. Subjects were sampled by multistage cluster sampling. The average ratio of 8-OHdG to creatinine was 4.7±4.1.No significant difference of 8-OHdG was observed between boys and girls in this study.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Evaluation of Oxidative DNA Damage and Its Relation with Anthropometric Indices in Healthy Adolescents
AU  - Farzaneh Bagherzadeh
AU  - Mehrangiz Ebrahimi-Mameghani
AU  - Mohammad Asghari Jafarabadi
AU  - Zahra Aslani
AU  - Sare Edalati
Y1  - 2015/03/02
PY  - 2015
N1  - https://doi.org/10.11648/j.ajbio.s.2015030202.11
DO  - 10.11648/j.ajbio.s.2015030202.11
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 21
EP  - 25
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ajbio.s.2015030202.11
AB  - Reactive oxygen species (ROS) and oxidative stress (OS) have important role in prevention, initiation and progression of chronic diseases from early childhood, but OS status in healthy young subjects and appropriate methods for its measurement have been remained unclear. Evaluation of urinary biomarker set for OS has not been well documented in Iran. In this study, evaluation of OS from urinary biomarker in healthy adolescents and its relevance to anthropometric index were investigated. Forty- hundred students aged 13 and 19 years old participated in this study. 8-hydroxy-2ʹ-deoxyguanosine (8-OHdG) as marker of oxidative DNA damage was measured in adolescents and also its relation with age, sex and body mass index was studied. Subjects were sampled by multistage cluster sampling. The average ratio of 8-OHdG to creatinine was 4.7±4.1.No significant difference of 8-OHdG was observed between boys and girls in this study.
VL  - 4
IS  - 2-1
ER  -

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