Intravascular hemolysis, particularly blackwater fever is a rare but severe clinical syndrome, occurring after ingestion of antimalarials. Diagnosis relies on clinical symptoms and on the color of the urines. A resurgence of this affection which occurred frequently during the colonization has lately been noticed. We report a case of blackwater fever complicated with severe renal failure and severe acute hemolysis having evolved favorably with modest resuscitation means. A 16 year teenager from Burkina Faso, who regularly takes quinine to treat malaria presumptive access, presented the waning of an undocumented malaria, fever, consciousness disorders, anemia, jaundice and blackish urine. The thick drop, blood cultures and urine cultures were negative. Biology revealed leukocytosis 14,000/mm3, anemia in 6.5 g/dL, total bilirubin 80 μmol/L and kidney failure at 13 mmol/L of azotemia and 700 μmol/L creatinine. The evolution was favorable after a modest resuscitation. Blackwater fever still exists in our daily practice. We need to think about in front of sudden onset of hemolysis and acute renal failure with dark-red colored urine during treatment of malaria. We are facing an issue thus a rational use of antimalarials is necessary.
| Published in | Journal of Diseases and Medicinal Plants (Volume 2, Issue 1) |
| DOI | 10.11648/j.jdmp.20160201.12 |
| Page(s) | 5-7 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2016. Published by Science Publishing Group |
Blackwater Fever, Malaria, Hemoglobinuria, Quinine
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APA Style
Barro Sie Drissa, Traore Ibrahim Alain, Sawadogo Appolinaire, Ki Kelan Bertille, Kamboule Bebard Euloges, et al. (2016). Blackwater Fever (BWF): About a Case in the Intensive Care Unit of the Hospital University Centre Souro-Sanou in Bobo-Dioulasso, Burkina Faso. Journal of Diseases and Medicinal Plants, 2(1), 5-7. https://doi.org/10.11648/j.jdmp.20160201.12
ACS Style
Barro Sie Drissa; Traore Ibrahim Alain; Sawadogo Appolinaire; Ki Kelan Bertille; Kamboule Bebard Euloges, et al. Blackwater Fever (BWF): About a Case in the Intensive Care Unit of the Hospital University Centre Souro-Sanou in Bobo-Dioulasso, Burkina Faso. J. Dis. Med. Plants 2016, 2(1), 5-7. doi: 10.11648/j.jdmp.20160201.12
AMA Style
Barro Sie Drissa, Traore Ibrahim Alain, Sawadogo Appolinaire, Ki Kelan Bertille, Kamboule Bebard Euloges, et al. Blackwater Fever (BWF): About a Case in the Intensive Care Unit of the Hospital University Centre Souro-Sanou in Bobo-Dioulasso, Burkina Faso. J Dis Med Plants. 2016;2(1):5-7. doi: 10.11648/j.jdmp.20160201.12
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Download@article{10.11648/j.jdmp.20160201.12,
author = {Barro Sie Drissa and Traore Ibrahim Alain and Sawadogo Appolinaire and Ki Kelan Bertille and Kamboule Bebard Euloges and Rouamba Alexis and Bayala Bale},
title = {Blackwater Fever (BWF): About a Case in the Intensive Care Unit of the Hospital University Centre Souro-Sanou in Bobo-Dioulasso, Burkina Faso},
journal = {Journal of Diseases and Medicinal Plants},
volume = {2},
number = {1},
pages = {5-7},
doi = {10.11648/j.jdmp.20160201.12},
url = {https://doi.org/10.11648/j.jdmp.20160201.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20160201.12},
abstract = {Intravascular hemolysis, particularly blackwater fever is a rare but severe clinical syndrome, occurring after ingestion of antimalarials. Diagnosis relies on clinical symptoms and on the color of the urines. A resurgence of this affection which occurred frequently during the colonization has lately been noticed. We report a case of blackwater fever complicated with severe renal failure and severe acute hemolysis having evolved favorably with modest resuscitation means. A 16 year teenager from Burkina Faso, who regularly takes quinine to treat malaria presumptive access, presented the waning of an undocumented malaria, fever, consciousness disorders, anemia, jaundice and blackish urine. The thick drop, blood cultures and urine cultures were negative. Biology revealed leukocytosis 14,000/mm3, anemia in 6.5 g/dL, total bilirubin 80 μmol/L and kidney failure at 13 mmol/L of azotemia and 700 μmol/L creatinine. The evolution was favorable after a modest resuscitation. Blackwater fever still exists in our daily practice. We need to think about in front of sudden onset of hemolysis and acute renal failure with dark-red colored urine during treatment of malaria. We are facing an issue thus a rational use of antimalarials is necessary.},
year = {2016}
}
TY - JOUR T1 - Blackwater Fever (BWF): About a Case in the Intensive Care Unit of the Hospital University Centre Souro-Sanou in Bobo-Dioulasso, Burkina Faso AU - Barro Sie Drissa AU - Traore Ibrahim Alain AU - Sawadogo Appolinaire AU - Ki Kelan Bertille AU - Kamboule Bebard Euloges AU - Rouamba Alexis AU - Bayala Bale Y1 - 2016/02/19 PY - 2016 N1 - https://doi.org/10.11648/j.jdmp.20160201.12 DO - 10.11648/j.jdmp.20160201.12 T2 - Journal of Diseases and Medicinal Plants JF - Journal of Diseases and Medicinal Plants JO - Journal of Diseases and Medicinal Plants SP - 5 EP - 7 PB - Science Publishing Group SN - 2469-8210 UR - https://doi.org/10.11648/j.jdmp.20160201.12 AB - Intravascular hemolysis, particularly blackwater fever is a rare but severe clinical syndrome, occurring after ingestion of antimalarials. Diagnosis relies on clinical symptoms and on the color of the urines. A resurgence of this affection which occurred frequently during the colonization has lately been noticed. We report a case of blackwater fever complicated with severe renal failure and severe acute hemolysis having evolved favorably with modest resuscitation means. A 16 year teenager from Burkina Faso, who regularly takes quinine to treat malaria presumptive access, presented the waning of an undocumented malaria, fever, consciousness disorders, anemia, jaundice and blackish urine. The thick drop, blood cultures and urine cultures were negative. Biology revealed leukocytosis 14,000/mm3, anemia in 6.5 g/dL, total bilirubin 80 μmol/L and kidney failure at 13 mmol/L of azotemia and 700 μmol/L creatinine. The evolution was favorable after a modest resuscitation. Blackwater fever still exists in our daily practice. We need to think about in front of sudden onset of hemolysis and acute renal failure with dark-red colored urine during treatment of malaria. We are facing an issue thus a rational use of antimalarials is necessary. VL - 2 IS - 1 ER -
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