Systemic mycosis caused by fungi (or dimorphic fungi) such as Histoplasma, emmonsia, candida & penicillium has emerged as an important opportunistic fungal infection in immunocompromised patient in South- East Asia. Several cases of opportunistic fungal infection has been reported but cytological diagnosis of disseminated (dimorphic) fungal infection has been reported in very few cases. Cytological diagnosis of these infections depending on the morphological characteristics has always been a challenge to practising cytologists. A case of rare disseminated fungal infection reported in a 45 year old seropositive male who is noncompliant on ART presented with ulcer over palate, fever, weight loss, occasional per rectal bleeding. On examination having bilateral cervical lymphadenopathy and hepatomegaly. On investigation- anaemia, high ESR, deranged liver function test, CD4 count 16/cumm, USG showed hepatomegaly, underwent FNAC cervical lymphnodes and guided FNAC of liver, which showed these organisms, but no pathogens were found with classical microbiological procedure. Patient was treated with itraconazole and amphotericine and showed improvement. This case illustrate the utility of FNAC in early diagnosis & management of rare infection & it also highlight the combined role of molecular technique and FNAC as an interdisciplinary approach for management of patient.
| Published in |
Science Journal of Clinical Medicine (Volume 4, Issue 4-1)
This article belongs to the Special Issue Latest Different Concepts of Gynaecology |
| DOI | 10.11648/j.sjcm.s.2015040401.15 |
| Page(s) | 19-22 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2015. Published by Science Publishing Group |
Dimorphic Fungal Infection, FNAC Lymph Node, Seropositive
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APA Style
Chitresh Yadav, Nandini N. M., Shruti M. K., Sowmya G. S., M. R. Shivaprakash, et al. (2015). Cytodiagnosis of Dimorphic Fungi with Disseminated Infection in a HIV Positive Patient – A Diagnostic Dilemma. Science Journal of Clinical Medicine, 4(4-1), 19-22. https://doi.org/10.11648/j.sjcm.s.2015040401.15
ACS Style
Chitresh Yadav; Nandini N. M.; Shruti M. K.; Sowmya G. S.; M. R. Shivaprakash, et al. Cytodiagnosis of Dimorphic Fungi with Disseminated Infection in a HIV Positive Patient – A Diagnostic Dilemma. Sci. J. Clin. Med. 2015, 4(4-1), 19-22. doi: 10.11648/j.sjcm.s.2015040401.15
AMA Style
Chitresh Yadav, Nandini N. M., Shruti M. K., Sowmya G. S., M. R. Shivaprakash, et al. Cytodiagnosis of Dimorphic Fungi with Disseminated Infection in a HIV Positive Patient – A Diagnostic Dilemma. Sci J Clin Med. 2015;4(4-1):19-22. doi: 10.11648/j.sjcm.s.2015040401.15
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Download@article{10.11648/j.sjcm.s.2015040401.15,
author = {Chitresh Yadav and Nandini N. M. and Shruti M. K. and Sowmya G. S. and M. R. Shivaprakash and G. V. Manjunath},
title = {Cytodiagnosis of Dimorphic Fungi with Disseminated Infection in a HIV Positive Patient – A Diagnostic Dilemma},
journal = {Science Journal of Clinical Medicine},
volume = {4},
number = {4-1},
pages = {19-22},
doi = {10.11648/j.sjcm.s.2015040401.15},
url = {https://doi.org/10.11648/j.sjcm.s.2015040401.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.s.2015040401.15},
abstract = {Systemic mycosis caused by fungi (or dimorphic fungi) such as Histoplasma, emmonsia, candida & penicillium has emerged as an important opportunistic fungal infection in immunocompromised patient in South- East Asia. Several cases of opportunistic fungal infection has been reported but cytological diagnosis of disseminated (dimorphic) fungal infection has been reported in very few cases. Cytological diagnosis of these infections depending on the morphological characteristics has always been a challenge to practising cytologists. A case of rare disseminated fungal infection reported in a 45 year old seropositive male who is noncompliant on ART presented with ulcer over palate, fever, weight loss, occasional per rectal bleeding. On examination having bilateral cervical lymphadenopathy and hepatomegaly. On investigation- anaemia, high ESR, deranged liver function test, CD4 count 16/cumm, USG showed hepatomegaly, underwent FNAC cervical lymphnodes and guided FNAC of liver, which showed these organisms, but no pathogens were found with classical microbiological procedure. Patient was treated with itraconazole and amphotericine and showed improvement. This case illustrate the utility of FNAC in early diagnosis & management of rare infection & it also highlight the combined role of molecular technique and FNAC as an interdisciplinary approach for management of patient.},
year = {2015}
}
TY - JOUR T1 - Cytodiagnosis of Dimorphic Fungi with Disseminated Infection in a HIV Positive Patient – A Diagnostic Dilemma AU - Chitresh Yadav AU - Nandini N. M. AU - Shruti M. K. AU - Sowmya G. S. AU - M. R. Shivaprakash AU - G. V. Manjunath Y1 - 2015/08/03 PY - 2015 N1 - https://doi.org/10.11648/j.sjcm.s.2015040401.15 DO - 10.11648/j.sjcm.s.2015040401.15 T2 - Science Journal of Clinical Medicine JF - Science Journal of Clinical Medicine JO - Science Journal of Clinical Medicine SP - 19 EP - 22 PB - Science Publishing Group SN - 2327-2732 UR - https://doi.org/10.11648/j.sjcm.s.2015040401.15 AB - Systemic mycosis caused by fungi (or dimorphic fungi) such as Histoplasma, emmonsia, candida & penicillium has emerged as an important opportunistic fungal infection in immunocompromised patient in South- East Asia. Several cases of opportunistic fungal infection has been reported but cytological diagnosis of disseminated (dimorphic) fungal infection has been reported in very few cases. Cytological diagnosis of these infections depending on the morphological characteristics has always been a challenge to practising cytologists. A case of rare disseminated fungal infection reported in a 45 year old seropositive male who is noncompliant on ART presented with ulcer over palate, fever, weight loss, occasional per rectal bleeding. On examination having bilateral cervical lymphadenopathy and hepatomegaly. On investigation- anaemia, high ESR, deranged liver function test, CD4 count 16/cumm, USG showed hepatomegaly, underwent FNAC cervical lymphnodes and guided FNAC of liver, which showed these organisms, but no pathogens were found with classical microbiological procedure. Patient was treated with itraconazole and amphotericine and showed improvement. This case illustrate the utility of FNAC in early diagnosis & management of rare infection & it also highlight the combined role of molecular technique and FNAC as an interdisciplinary approach for management of patient. VL - 4 IS - 4-1 ER -
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