Human body possesses remarkably efficient mechanisms for fighting bacterial infection. Some of these mechanisms are still enigmatic and unclear. Contrary to popular belief, most microorganisms are less capable of provoking disease when injected intravenously than when administered by any other route. Available scientific data can’t convincingly explain this phenomenon. Taking into account that antibiotic resistance is a serious and growing phenomenon in contemporary medicine many available blind spots regarding human antibacterial defense should be studied as soon and as much as possible. The main purpose of this special issue is collecting and disseminating advanced research data in the field of antibacterial defense for better understanding of human antibacterial immunity. Original research papers are solicited in any aspect of human antibacterial immunity.

Aims and scope:

1. Antibacterial cellular immunity in bloodstream
2. Antibacterial humoral immunity in bloodstream
3. Local antibacterial cellular immunity (out of blood circulation) in skin and tissues
4. Local antibacterial humoral immunity (out of blood circulation) in skin and tissues
5. Cellular immunity in the lungs, liver, spleen, thymus and lymph nodes
6. Humoral immunity in the lungs, liver, spleen, thymus and lymph nodes
7. The mechanisms of bacteria survival and dissemination in human body